{"id":1891,"date":"2026-04-20T14:53:21","date_gmt":"2026-04-20T06:53:21","guid":{"rendered":"http:\/\/hegutf.com\/?post_type=product&p=1891"},"modified":"2026-05-29T13:53:39","modified_gmt":"2026-05-29T05:53:39","slug":"stainless-steel-chromatography-column","status":"publish","type":"product","link":"https:\/\/hegutf.com\/en\/product\/stainless-steel-chromatography-column\/","title":{"rendered":"Stainless Steel Chromatography Columns"},"content":{"rendered":"
\n

(1) Product Overview<\/h3>\n
Stainless steel chromatography columns are core separation and purification devices designed for the entire process\u2014from sample loading, chromatography, elution, detection, and collection to cleaning. Based on the principle of chromatographic separation, they achieve efficient separation, purification, and enrichment of target components in materials through the specific adsorption and desorption of the target components by the chromatographic medium. The equipment is constructed from a single piece of 304\/316L stainless steel with a scientifically sound and rational design, allowing for precise control of various process parameters. It offers high separation efficiency and good reproducibility, complies with GMP pharmaceutical standards and relevant FDA requirements, and is widely used in the biopharmaceutical, plant extraction, food and health supplement, and chemical industries. It is suitable for laboratory, pilot-scale, and full-scale production settings and can handle the purification and separation of various materials, including proteins, antibodies, polysaccharides, and natural products.<\/div>\n

(2) Structural Configuration Description<\/h3>\n
Stainless steel chromatography columns consist of a column core and\u914d\u5957 auxiliary components. They are designed entirely from sanitary-grade stainless steel and can be configured with basic auxiliary components as needed:<\/div>\n
    \n
  • \n
    Core Column: Made of 304\/316L stainless steel in a single-piece construction, with a polished inner wall that leaves no dead spots. Compatible with various chromatography modes, including gel filtration, ion exchange, hydrophobic, and affinity chromatography, ensuring separation accuracy and stability.<\/div>\n<\/li>\n
  • \n
    Compatible Components: Can be used with an injection valve, multi-channel buffer inlet, and gradient mixer to enable precise sample loading and gradient elution control<\/div>\n<\/li>\n
  • \n
    Online Detection Compatibility: Can be used with a UV detector (multiple wavelengths available from 190\u2013400 nm), a pH sensor, and a conductivity sensor to monitor eluting components in real time and accurately identify target peaks.<\/div>\n<\/li>\n
  • \n
    Collection Compatibility: Compatible with component collectors (suitable for 15 mL test tubes, 50 mL centrifuge tubes, and other sizes), supports both peak collection and time-based collection modes, minimizing component loss<\/div>\n<\/li>\n
  • \n
    Auxiliary Systems: Can be equipped with a CIP (Clean-in-Place) system, a bubble detector, and a backpressure valve to ensure equipment cleanliness and stable operation, reduce dead volume in the piping, and improve separation efficiency.<\/div>\n<\/li>\n<\/ul>\n

    (3) Key Features<\/h3>\n
      \n
    • \n
      Suitable for the entire workflow: Seamlessly integrates sample loading, chromatography, elution, detection, collection, and cleaning; features convenient manual operation and flexibly adapts to different production needs.<\/div>\n<\/li>\n
    • \n
      High separation precision: The column is scientifically designed with smooth inner walls and no dead spots, allowing for precise control of the elution gradient and effective separation of trace components; the purification purity can reach 95% or higher.<\/div>\n<\/li>\n
    • \n
      Durable Construction: Made of one-piece 304\/316L stainless steel, it is corrosion-resistant, break-resistant, ensures stable long-term operation, and is easy to maintain.<\/div>\n<\/li>\n
    • \n
      High Compliance: The column body and wetted parts are made of 304\/316L stainless steel (food-grade or pharmaceutical-grade options available), with polished inner and outer surfaces, in compliance with GMP and ASME BPE production standards, and meeting the compliance requirements of the pharmaceutical industry.<\/div>\n<\/li>\n
    • \n
      Wide Range of Applications: Suitable for various modes, including gel filtration, ion exchange, hydrophobic chromatography, and affinity chromatography, and capable of processing a wide range of materials, such as proteins, antibodies, polysaccharides, alkaloids, and natural products.<\/div>\n<\/li>\n
    • \n
      Easy to Operate: With a well-designed structure and simple, intuitive manual controls, even beginners can get started quickly. No complex setup is required, and the system operates stably and reliably.<\/div>\n<\/li>\n<\/ul>\n

      (4) Technical Specifications<\/h3>\n
      \n\n\n\n<\/colgroup>\n\n\n\n\n\n\n\n\n\n\n\n
      \n
      Parameter Items<\/div>\n<\/td>\n
      		\n
      Specifications<\/div>\n<\/td>\n<\/tr>\n
      \n
      Equipment Name<\/div>\n<\/td>\n
      		\n
      Stainless Steel Chromatography Columns<\/div>\n<\/td>\n<\/tr>\n
      \n
      Chromatography Mode<\/div>\n<\/td>\n
      		\n
      A variety of modes are available, including gel filtration, ion exchange, hydrophobic, and affinity.<\/div>\n<\/td>\n<\/tr>\n
      \n
      <\/div>\n<\/td>\n
      		\n
      0.01\u20133,600 mL\/min (customizable by model; supports gradient elution)<\/div>\n<\/td>\n<\/tr>\n
      \n
      Testing System<\/div>\n<\/td>\n
      		\n
      Can be used with a UV detector (190\u2013400 nm, accuracy \u00b11 nm), pH meter (0\u201314, \u00b10.1), and conductivity meter (1 \u03bcS\/cm\u2013999 mS\/cm)<\/div>\n<\/td>\n<\/tr>\n
      \n
      Column Material<\/div>\n<\/td>\n
      		\n
      304\/316L stainless steel (food-grade\/pharmaceutical-grade options available), with polished inner and outer surfaces, compliant with USP Class VI certification, and meeting regulatory requirements for the pharmaceutical and herbal extract industries<\/div>\n<\/td>\n<\/tr>\n
      \n
      Control Method<\/div>\n<\/td>\n
      		\n
      Manual control, easy to operate, and allows for precise adjustment of process parameters<\/div>\n<\/td>\n<\/tr>\n
      \n
      Collection Methods<\/div>\n<\/td>\n
      		\n
      Compatible with collectors; supports peak collection and time-based collection; suitable for collecting samples in 120-well test tubes or 42-well centrifuge tubes<\/div>\n<\/td>\n<\/tr>\n
      \n
      Work-related stress<\/div>\n<\/td>\n
      		\n
      0\u201350 bar (adjustable as needed)<\/div>\n<\/td>\n<\/tr>\n
      \n
      Supporting Systems<\/div>\n<\/td>\n
      		\n
      Compatible with CIP (Clean-in-Place) systems, bubble detection, and buffer pretreatment systems<\/div>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
      \n

      III. Comparison with Traditional Chromatography Columns<\/h2>\n
      Compared to traditional glass chromatography columns and non-stainless steel chromatography columns, the key advantages of stainless steel chromatography columns are clear, helping you quickly select the right model:<\/div>\n
      \n\n\n\n\n<\/colgroup>\n\n\n\n\n\n\n\n\n
      \n
      Comparison Items<\/div>\n<\/td>\n
      		\n
      Stainless Steel Chromatography Columns<\/div>\n<\/td>\n
      		\n
      Traditional Glass\/Non-Stainless Steel Chromatography Columns<\/div>\n<\/td>\n<\/tr>\n
      \n
      Material Properties<\/div>\n<\/td>\n
      		\n
      Made of 304\/316L stainless steel, it is corrosion-resistant and durable. The interior walls are polished with no hard-to-reach areas, ensuring compliance with food-grade standards.<\/div>\n<\/td>\n
      		\n
      Glass is prone to breakage, while non-stainless steel materials have poor corrosion resistance, are prone to residue buildup on the inner walls, and lack adequate hygiene.<\/div>\n<\/td>\n<\/tr>\n
      \n
      Separation Accuracy<\/div>\n<\/td>\n
      		\n
      The column is scientifically designed to allow precise control of the elution gradient, resulting in high separation purity (\u226595%) and good reproducibility.<\/div>\n<\/td>\n
      		\n
      Low column precision, significant elution control errors, low separation resolution, and poor reproducibility<\/div>\n<\/td>\n<\/tr>\n
      \n
      Compliance<\/div>\n<\/td>\n
      		\n
      Complies with GMP and FDA regulations; materials meet compliance standards; meets the regulatory requirements of the pharmaceutical industry<\/div>\n<\/td>\n
      		\n
      The material does not meet the compliance requirements of the pharmaceutical industry and has limited compatibility.<\/div>\n<\/td>\n<\/tr>\n
      \n
      Efficiency and Losses<\/div>\n<\/td>\n
      		\n
      Allows for continuous operation, convenient manual collection, minimal loss of components, and high equipment utilization<\/div>\n<\/td>\n
      		\n
      Intermittent operation and manual collection can lead to loss of components, low efficiency, and damage that results in material waste.<\/div>\n<\/td>\n<\/tr>\n
      \n
      Suitable Scenarios<\/div>\n<\/td>\n
      		\n
      Suitable for laboratory, pilot-scale, and full-scale production, capable of handling a wide range of materials and chromatography modes<\/div>\n<\/td>\n
      		\n
      Suitable only for small-batch laboratory samples; prone to breakage; difficult to scale up and produce on a large scale.<\/div>\n<\/td>\n<\/tr>\n
      \n
      Ease of Maintenance<\/div>\n<\/td>\n
      		\n
      Simple in design, easy to maintain and replace, and compatible with CIP (Clean-in-Place) systems, reducing the cost of manual cleaning<\/div>\n<\/td>\n
      		\n
      Non-modular design; the glass material is prone to breakage; manual disassembly and cleaning are required, resulting in a heavy workload and high maintenance costs.<\/div>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"
      \n
      Stainless steel chromatography columns are designed for the entire process\u2014from sample loading, chromatography, and elution to detection and collection. They offer high separation precision and stable performance. Made of 304\/316L stainless steel, these columns are suitable for the purification of target compounds in the pharmaceutical, herbal extract, and biotechnology industries, ensuring compliance, controllability, and ease of operation.<\/div>\n<\/div>","protected":false},"featured_media":1918,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[95],"product_tag":[],"class_list":["post-1891","product","type-product","status-publish","has-post-thumbnail","product_cat-separation-purification-equipment","first","instock","shipping-taxable","product-type-simple"],"yoast_head":"\n\u4e0d\u9508\u94a2\u5c42\u6790\u67f1_\u6811\u8102\u7cbe\u5236\u8bbe\u5907\u5b9a\u5236-\u6838\u8c37\u5929\u5bcc<\/title>\n<meta name=\"description\" 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