Microporous Membrane Cartridge Filter

Cylindrical Microporous Membrane Filter | Stainless Steel Multi-Core Folded Filter Cartridge Sterilizing Precision Filtration Equipment

💡Microporous membrane cartridge filter with a 316L stainless steel housing, equipped with a pleated microporous filter element, providing 0.1–5 μm precision absolute filtration, and supporting SIP (sterilization-in-place). It is used for the final sterilization and impurity removal of pharmaceutical solutions, water for injection, biopharmaceuticals, and high-purity solvents.

I. Product Introduction

The microporous membrane cartridge filter uses a pleated microporous membrane filter element housed in a stainless steel cylinder. It provides absolute filtration (0.1–5 μm) for liquids or gases and is the preferred final filtration device for high-demand processes such as water for injection, large-volume parenteral solutions, and biopharmaceuticals.

II. How It Works

The feed solution enters from the outside of the filter cartridge, passes through the filter membrane (pore size 0.1–5 μm), and enters the center tube of the filter cartridge, while particles and bacteria are retained on the surface or within the filter membrane (absolute filtration). The filter cartridge undergoes integrity testing (bubble point, diffusion flow) to ensure it meets sterile filtration standards.

III. Main Structural Components

IV. Core Advantages

✅ Absolute filtration, reliable bacteria removal

All filter cartridges undergo integrity testing before leaving the factory. The 0.22 μm model consistently meets sterile filtration standards, thoroughly retaining bacteria, particles, and impurities, and satisfying the requirements of high-end cleanroom production.

✅ High flow rate, low pressure drop

The use of a pleated filter membrane structure significantly increases the effective filtration area; a single 10-inch cartridge can achieve an effective filtration area of up to 0.6 square meters. It features a fast filtration rate, low operating pressure drop, and is resistant to membrane clogging, resulting in high production efficiency.

✅ Heat-resistant and reusable after sterilization

The entire unit supports 121°C/30-minute in-line SIP steam sterilization and is also compatible with split-type autoclave sterilization. It is heat- and corrosion-resistant, can be reused repeatedly, and has a long service life.

✅ No fiber shedding; does not contaminate the material

Features an integrated, one-piece filtration media structure made of PP, PES, and PTFE, ensuring no fibers or debris shed and eliminating the risk of secondary contamination of materials. Suitable for the production of high-purity materials and sterile pharmaceutical solutions.

✅ Complete documentation; supports GMP validation

We can provide a complete set of validation documentation, including bacterial challenge tests, extractables testing, and toxicity reports, to help you easily pass GMP and FDA inspections for pharmaceutical and biotech companies.

V. Typical Use Cases

✅ Pharmaceutical-Grade Pure Water: Water for Injection (WFI) Final Sterilizing Filtration

Used at the end of pharmaceutical pure water systems for 0.22 μm precision sterilization to ensure that water for injection is clean and sterile.

✅ Injectable solutions and large-volume infusions: End-point sterilizing filtration prior to filling

Oral solutions, large-volume parenteral solutions, and injectable solutions undergo precision filtration prior to filling to remove bacteria and minute impurities, ensuring the quality of the finished pharmaceutical solutions.

✅ Biopharmaceuticals: Filtration of protein solutions, vaccines, and blood products

Designed for the precise, low-temperature sterilization of highly active biological materials without compromising their activity, enabling sterile preparation.

✅ Fine Chemicals: Electronic chemicals, impurity removal from high-purity solvents

Filters out microscopic particulate impurities from high-purity reagents and electronic solvents to improve material purity.

✅ Process gases: compressed air, nitrogen sterilization filtration

When paired with a hydrophobic PTFE filter element, it effectively removes moisture, impurities, and bacteria from various process gases.

✅ Fermentation Industry: Sterile Pretreatment of Fermentation Feed Gas

Using a 0.01-micrometer hydrophobic membrane filter cartridge to trap airborne bacteria, it provides a sterile air supply to the fermenter and eliminates the risk of contamination.

VI. Basic Technical Specifications

VII. Optional Configurations

Optional features include an automatic drain valve, quick-opening clamp fittings, a sterile sampling port, a filter integrity tester, and explosion-proof piping fittings, making it suitable for various production conditions in sterile and explosion-proof facilities.

VIII. Service Commitment

Filter cartridge materials, housing specifications, and equipment configurations can be customized to meet your needs. The complete equipment set comes with comprehensive GMP validation documentation. We provide end-to-end services, including professional equipment selection, on-site installation, guidance on filter cartridge replacement, and equipment operation and maintenance training. We ship nationwide and offer a 24-hour rapid response for after-sales service in Chongqing.

🔗 Recommended Compatible Devices

Reference Guide for Selecting Production Line Equipment:
✅ Front-end ingredient handling equipment:Mixing and Storage Tanks
✅ Complete line of cleaning equipment:Support Systems
✅ Downstream concentration and purification:Concentration equipment