Dosing Tank, Concentrate Tank, Dilution Tank

Fully Automatic Liquid Formulation System | Integrated Pharmaceutical Liquid Formulation Equipment for Concentrate and Dilute Formulations

💡The solution preparation system consists of a complete set of concentrate and dilute tanks, featuring 304/316L sanitary-grade mirror-finished tanks. It handles the entire process—from dissolving and concentrating materials to dilution and volume adjustment—and is equipped with CIP cleaning capabilities. The system complies with cGMP standards and is suitable for the preparation of liquid formulations in the pharmaceutical, food, and biopharmaceutical industries.

I. Product Introduction

The solution preparation system consists of a concentrate tank and a dilute solution tank, and is used for dissolving, mixing, formulating, and adjusting the volume of liquid materials. The concentrate tank is used for initial preparation of high-concentration solutions, while the dilute solution tank is used for further dilution to the target concentration. The system is widely used in the pharmaceutical, biopharmaceutical, food and beverage, and fine chemicals industries.

II. How It Works

The material is fed into the tank through the feed port; the agitator provides mixing and shear forces, and the jacket can be circulated with steam or cooling water for temperature control. After a high-concentration solution is prepared in the concentrate tank, it is transferred via piping to the dilute tank, where a solvent is added to dilute it to the specified concentration. Once thoroughly mixed, the solution is discharged through the outlet to downstream filling or storage processes.

III. Main Structural Components

✅ Stainless steel tank (SUS304/316L, inner wall mirror-polished to Ra ≤ 0.4 μm)

Pharmaceutical-grade stainless steel tanks with high-precision mirror polishing that leaves no blind spots, in compliance with clean production polishing standards.

✅ Agitation system (paddle, anchor, or magnetic stirring)

Conventional mechanical stirring and sealed magnetic stirring are available as options to meet various cleanroom and explosion-proof production requirements.

✅ Jacket/Coil (for heating or cooling)

Hot and cold media are fed into the heat exchanger, enabling rapid temperature changes and maintaining a stable process temperature.

✅ Insulation layer (polyurethane or rock wool)

Minimize the impact of ambient temperature fluctuations and reduce energy consumption for heating and cooling.

✅ Manholes, sight glasses, breather valves, level gauges

For easy maintenance and inspection, the respirator prevents contamination by bacteria, and the liquid level is monitored in real time to track inventory.

✅ Temperature sensor, pH meter (optional)

Real-time online monitoring of physical and chemical parameters ensures that the pharmaceutical solutions meet the required specifications.

✅ CIP Cleaning Ball

360° all-around spraying for online cleaning of the entire solution preparation pipeline and tank system.

IV. Core Advantages

✅ Sanitary-grade design: No hard-to-reach areas, easy to clean, and compliant with cGMP and FDA requirements.

The tank features smooth transitions with no dead corners where material can accumulate, meeting FDA acceptance standards for pharmaceutical exports.

✅ Precise Temperature Control: The jacket features a large heat exchange surface area, which, combined with the automatic control system, achieves an accuracy of ±1°C.

Automated temperature control prevents temperature fluctuations from affecting the quality of the pharmaceutical solution.

✅ Multiple mixing modes: Select different impellers based on viscosity to achieve high mixing uniformity.

Both high- and low-viscosity materials can be processed using the appropriate mixing configuration, ensuring thorough dissolution without clumping.

✅ Modular configuration: Can be integrated with load cells, variable-frequency speed control, and online cleaning.

Functional modules can be added or removed as needed to accommodate both semi-automatic and fully automatic production lines.

✅ Complete range of sizes: 50L–20,000L; custom sizes available.

The total solution preparation volume and port layout are customized to meet the specific requirements of the workshop site.

V. Typical Use Cases

✅ Pharmaceutical Manufacturing: Preparation of Water for Injection, Large-Volume Injections, and Oral Solutions

Complete production of concentrated and diluted solutions for injections and oral liquids.

✅ Bioengineering: Preparation of culture media, buffers, and purified water

The aseptic ingredient preparation process prior to fermentation.

✅ Food: Blending of beverage syrups, dairy products, and flavorings

Production of beverages and dairy concentrates.

✅ Chemical Industry: Formulation of fine chemicals and electronic chemicals

Closed-system preparation of electronic reagents and fine chemical solutions.

VI. Optional Configurations

✅ Load Cells (Mettler Toledo)

High-precision online weighing and feeding ensure accurate and controllable batching and metering.

✅ Magnetic stirring (leak-free)

No mechanical seals and zero leakage; suitable for aseptic and organic solvent applications.

✅ Automatic Temperature Control System (PLC + Steam Valve)

The system is program-controlled and automatically opens and closes the valves for the hot and cold media.

✅ Online pH/Conductivity Monitoring

Real-time online monitoring of pharmaceutical solution parameters, with alerts for non-compliance.

✅ Explosion-proof design (for organic solvents)

Explosion-proof motor and electrical control system for the entire unit; specifically configured for Class A explosion-proof workshops.

VII. Key Technical Specifications

VIII. Service Commitment

We provide end-to-end services covering the design of complete solution preparation solutions, equipment manufacturing, pipeline layout, on-site installation and commissioning, and GMP documentation coordination. The entire system is custom-built to meet specific requirements, with on-site delivery available nationwide and a 24-hour after-sales response in Chongqing.

🔗 Recommended Compatible Devices

Reference Guide for Selecting Production Line Equipment:
✅ Sterile Cleaning System:Support Systems
✅ Raw Material Storage Equipment:Mixing and Storage Tanks
✅ Filtration and Purification of Feed Solutions:Separation and Purification Equipment